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Time-resolved β-lactam cleavage by L1 metallo-β-lactamase

by Charlie Smith | Nov 30, 2022 | Science Highlights - BioCARS

Wilamowski, M., Sherrell, D. A., Kim, Y., Lavens, A., Henning, R. W., Lazarski, K., Shigemoto, A., Endres, M., Maltseva, N., Babnigg, G., Burdette, S. C., Srajer, V., and Joachimiak, A. (2022) Time-resolved β-lactam cleavage by L1 metallo-β-lactamase. Nat Commun 13,...

Light-Induced Protein Structural Dynamics in Bacteriophytochrome Revealed by Time-Resolved X-ray Solution Scattering

by Charlie Smith | May 27, 2022 | Science Highlights - BioCARS

Lee, S. J., Kim, T. W., Kim, J. G., Yang, C., Yun, S. R., Kim, C., Ren, Z., Kumarapperuma, I., Kuk, J., Moffat, K., Yang, X., and Ihee, H. (2022) Light-induced protein structural dynamics in bacteriophytochrome revealed by time-resolved x-ray solution scattering....

On-chip Crystallization and Large-Scale Serial Diffraction at Room Temperature

by Charlie Smith | Mar 11, 2022 | Science Highlights - BioCARS

Biju, L. M., Wang, C., Kang, W., Tom, I. P., Kumarapperuma, I., Yang, X., and Ren, Z. (2022) On-chip Crystallization and Large-Scale Serial Diffraction at Room Temperature. JoVE (Journal of Visualized Experiments) e63022.

Time-Resolved X-ray Scattering Studies of Proteins

by Charlie Smith | Oct 1, 2021 | Science Highlights - BioCARS

Cho, H. S., Schotte, F., Stadnytskyi, V., and Anfinrud, P. (2021) Time-resolved X-ray scattering studies of proteins. Current Opinion in Structural Biology 70, 99–107.

Effect of the Abolition of Intersubunit Salt Bridges on Allosteric Protein Structural Dynamics

by Charlie Smith | Jun 16, 2021 | Science Highlights - BioCARS

Choi, M., Kim, J. G., Muniyappan, S., Kim, H., Kim, T. W., Lee, Y., Lee, S. J., Kim, S. O., and Ihee, H. (2021) Effect of the abolition of intersubunit salt bridges on allosteric protein structural dynamics. Chem. Sci. 12, 8207–8217

Unfolding Bovine α-Lactalbumin with T-Jump: Characterizing Disordered Intermediates via Time-Resolved X-Ray Solution Scattering and Molecular Dynamics Simulations

by Charlie Smith | Mar 8, 2021 | Science Highlights - BioCARS

The protein folding process often proceeds through partially folded transient states. Therefore, a structural understanding of these disordered states is crucial for developing mechanistic models of the folding process. Characterization of unfolded states remains...
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