by Charlie Smith | Mar 11, 2022 | Science Highlights - BioCARS
Biju, L. M., Wang, C., Kang, W., Tom, I. P., Kumarapperuma, I., Yang, X., and Ren, Z. (2022) On-chip Crystallization and Large-Scale Serial Diffraction at Room Temperature. JoVE (Journal of Visualized Experiments) e63022.
by Charlie Smith | Oct 1, 2021 | Science Highlights - BioCARS
Cho, H. S., Schotte, F., Stadnytskyi, V., and Anfinrud, P. (2021) Time-resolved X-ray scattering studies of proteins. Current Opinion in Structural Biology 70, 99–107.
by Charlie Smith | Jun 16, 2021 | Science Highlights - BioCARS
Choi, M., Kim, J. G., Muniyappan, S., Kim, H., Kim, T. W., Lee, Y., Lee, S. J., Kim, S. O., and Ihee, H. (2021) Effect of the abolition of intersubunit salt bridges on allosteric protein structural dynamics. Chem. Sci. 12, 8207–8217
by Charlie Smith | Mar 8, 2021 | Science Highlights - BioCARS
The protein folding process often proceeds through partially folded transient states. Therefore, a structural understanding of these disordered states is crucial for developing mechanistic models of the folding process. Characterization of unfolded states remains...
by Charlie Smith | Sep 19, 2020 | Science Highlights - BioCARS
Direct observation of functional motions in protein structures is highly desirable for understanding how these nanomachineries of life operate at the molecular level. Because cryogenic temperatures are non-physiological and may prohibit or even alter protein...
by Charlie Smith | Feb 6, 2020 | Science Highlights - BioCARS
Small molecules such as molecular oxygen, nitric oxide, and carbon monoxide play important roles in life, and many proteins require the transport of small molecules to and from the bulk solvent for their function. Ligand migration within a protein molecule is expected...
