Time-resolved X-ray Science at BioCARS: Past, Present, and Future
2013 APS/CNM/EMC Users Meeting
Satellite Workshop (WK13), Thursday, May 9, 2013
The last major upgrade to the BioCARS 14ID beamline, completed in 2008, produced unprecedented time-resolved capabilities that have been exploited in many areas of X-ray science spanning biology, chemistry and physics. An APS-funded upgrade aims to further expand the capabilities of the 14ID beamline for the Physical Sciences. This workshop will bring together practitioners of time-resolved X-ray science to (1) discuss current capabilities and use of 14ID, and (2) discuss future challenges, needs and opportunities provided by the APS Upgrade to this diverse scientific community.
Organizers: Robert Henning (CARS, University of Chicago), Eric Dufresne (APS), Vukica Srajer (CARS, University of Chicago), and Philip Anfinrud (NIH)
Moffat Appointed Senior Advisor for Life Sciences at the APS
The Advanced Photon Source (APS) is the Western Hemisphere’s most powerful source of x-rays for research. It attracts more than 4,000 users from academia, industry, and government laboratories around the world each year for research in all fields of science. In particular, almost half of the user community is in the life sciences area. The appointment of a Senior Advisor for Life Sciences at the APS (SALSA) to provide a stronger linkage with the life sciences community has been recommended by APS review committees and has been a priority for APS management. Furthermore, ongoing preparations for a major upgrade to the APS require strategic decisions that will benefit from the advice provided by an expert in this field. Following the recommendation of a search committee composed of APS management and users, I am pleased to announce the appointment of Prof. Keith Moffat of the University of Chicago to this position.
Moffat to Receive ACA Patterson Award
BioCARS Principal Investigator Keith Moffat has been selected as the recipient of the 2011 Patterson Award, given by the American Crystallographic Association. The award, established in 1980 to honor A. Lindo Patterson, recognizes and encourages outstanding research in the structure of matter by diffraction methods, including significant contributions to the methodology of structure determination and/or innovative application of diffraction methods and/or elucidation of biological, chemical, geological, or physical phenomena using new structural information. Moffat will be honored for his work in pioneering ultrafast time resolved x-ray diffraction using synchrotron radiation to capture the function of fundamental protein processes at atomic resolution.
BioCARS Participates in Annual X-ray School
On June 16 and 17, 2010, BioCARS conducted two half-day experiments with total of 13 students from the National School on Neutron and X-ray Scattering School. Instructors Irina Koshelev and Vukica Srajer demonstrated time-resolved macromolecular crystallography using photoactive yellow protein crystals, as well as Laue data processing using the program Precognition. The two-week-long school is held annually at the Advanced Photon Source, Argonne National Laboratory and the Spallation Neutron Source, Oak Ridge National Laboratory. Featuring lectures, tutorials, and hands-on experience, the school trains graduate students on the utilization of major neutron and x-ray facilities.
- October 2009
Staff Member Contributes to Fiber Diffraction Workshop
BioCARS beamline scientist Robert Henning participated in a workshop on fiber diffraction hosted by BioCAT (APS beamline 18-ID). The event included a demonstration of fiber crystallography capabilities at BioCARS beamline 14-BM-C. BioCARS and BioCAT have complementary techniques for this type of study and have made collaborative arrangements under which users may work at both facilities.
- December 2008
Workshop Concludes Successfully
- July 2008
BioCARS to Host Workshop on Time-Resolved Macromolecular Crystallography
- April 2008
BioCARS Open House Celebrates Upgrade
- March 2008
New Tutorial Introduces Laue Data Processing at BioCARS
- December 2007
Commissioning Begins on 100ps Time-Resolved Experiments
- September 2007
100ps Picosecond Time Resolution In Sight at BioCARS
- September 2007
14-ID Upgrade Nears Completion
- April 2004
A New Phase for BioCARS Station BM-C
- July 2003
Generation and Use of 100 fs Hard X-ray Pulses: BioCARS Participation in the SPPS Project at SLAC/SSRL